Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26032503 | 0.96 | HSD17B10 (0.41) | POLBHSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL12092085 | 0.93 | HPGD (0.41) | POLBHSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL15697251 | 0.93 | POLB (0.38) | POLBHSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL13642705 | 0.93 | POLB (0.38) | POLBHSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL14701700 | 0.92 | HPGD (0.40) | POLBHSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL15017077 | 0.92 | HPGD (0.40) | POLBHSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL16245112 | 0.92 | HPGD (0.40) | POLBHSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL526532 | 0.92 | HPGD (0.40) | POLBHSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL20254025 | 0.92 | HPGD (0.40) | POLBHSD17B10SMN1; SMN2HPGDTSHR | |
| SCHEMBL15152064 | 0.92 | HPGD (0.40) | POLBHSD17B10SMN1; SMN2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10435509-B2 | Hetero type monodispersed polyethylene glycol, intermediate for production of hetero type monodispersed polyethylene glycol, methods for producing same, and hetero type monodispersed polyethylene glycol conjugate | TOHOKU TECHNO ARCH CO., LTD. (JP) | 2019-10-08 | — | — | US | disclosed |
| US-9394354-B2 | Haptens of paliperidone | JANSSEN PHARMACEUTICA NV (BE) | 2016-07-19 | — | — | US | disclosed |
| US-20140213767-A1 | HAPTENS OF PALIPERIDONE | ORTHO-CLINICAL DIAGNOSTICS, INC. (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213767-A1 | HAPTENS OF PALIPERIDONE | CD274, PIN1, LY96 | POLB 4241/4885HSD17B10 2566/4885SMN1; SMN2 3323/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.