Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818237 | 0.91 | ELANE (0.50) | ELANEALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL3438961 | 0.91 | CYP19A1 (0.49) | ELANEALDH1A1KDM4EHSD17B10CYP19A1 | |
| SCHEMBL3438962 | 0.89 | CYP19A1 (0.47) | ELANEALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL11956765 | 0.88 | ELANE (0.45) | ELANEALDH1A1KDM4EHSD17B10CYP19A1 | |
| SCHEMBL16326823 | 0.86 | ALDH1A1 (0.46) | ELANEALDH1A1KDM4EHSD17B10CYP19A1 | |
| SCHEMBL14707361 | 0.86 | ELANE (0.46) | ELANEALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL5318627 | 0.84 | SMN1; SMN2 (0.49) | ELANEALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL11437247 | 0.83 | CYP19A1 (0.52) | ELANEALDH1A1KDM4EHSD17B10CYP19A1 | |
| SCHEMBL8584306 | 0.83 | ALDH1A1 (0.46) | ELANEALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL29197615 | 0.83 | ALDH1A1 (0.46) | ELANEALDH1A1KDM4EHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140213688-A1 | Absorbable Multi-Putty Bone Cements and Hemostatic Compositions and Methods of Use | ABYRX, INC. (US) | 2014-07-31 | — | — | US | disclosed |