Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | PIKFYVE | Q9Y2I7 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.54 |
| ▸ | TUBB | P07437 | 4/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15908165 | 0.90 | PIKFYVE (0.73) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL16200790 | 0.84 | PIKFYVE (0.79) | ALDH1A1MAPTNPC1RAB9APIKFYVE | |
| SCHEMBL16768705 | 0.82 | PIKFYVE (0.67) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL37221912 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL7250379 | 0.81 | ALDH1A1 (0.73) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL19530799 | 0.81 | ALDH1A1 (0.60) | ALDH1A1MAPTNPC1RAB9APIKFYVE | |
| SCHEMBL16768710 | 0.81 | MEN1 (0.59) | ALDH1A1MAPTNPC1RAB9APIKFYVE | |
| SCHEMBL16711707 | 0.79 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL16711704 | 0.79 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDMAPTNPC1 | |
| SCHEMBL16768704 | 0.79 | PIKFYVE (0.75) | ALDH1A1KDM4EHPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9023871-B2 | Materials and Methods Useful to Induce Vacuolization, Cell Death, or a Combination Thereof | THE UNIVERSITY OF TOLEDO (US) | 2015-05-05 | — | — | US | disclosed |
| US-20140213615-A1 | Materials and Methods Useful to Induce Vacuolization, Cell Death, or a Combination Thereof | THE UNIVERSITY OF TOLEDO (US) | 2014-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140213615-A1 | Materials and Methods Useful to Induce Vacuolization, Cell Death, or a Combination Thereof | BECN1, BAD, BAX | ALDH1A1 4456/4885KDM4E 3784/4885HPGD 2406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.