SCHEMBL15908657

SCHEMBL15908657

c1ccc(-c2cc(-c3ccccc3)nc(-c3ccc4c(c3)c3cccc5c3n4-c3ccccc3C53c4ccccc4-c4ccccc43)n2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.36
MEN1 O00255 7/20 0.36
KMT2A Q03164 7/20 0.36
ALDH1A1 P00352 5/20 0.36
HPGD P15428 5/20 0.36
KDM4E B2RXH2 4/20 0.36
LMNA P02545 3/20 0.36
NTSR1 P30989 1/20 0.35
GLA P06280 1/20 0.34
CYP2C19 P33261 3/20 0.32
CYP1A2 P05177 2/20 0.32
CYP2C9 P11712 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
AGTR1 P30556 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
CYP3A4 P08684 1/20 0.32
GAA P10253 1/20 0.32
TDP1 Q9NUW8 2/20 0.32
MAPK10 P53779 1/20 0.32
ADORA2A P29274 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9883239 0.98 MEN1 (0.34) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL15908659 0.97 MEN1 (0.38) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL15908621 0.96 MEN1 (0.36) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL15908629 0.96 MEN1 (0.36) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL15908662 0.93 DUSP3 (0.31) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL15908655 0.93 MEN1 (0.35) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL24293390 0.92 PDK2 (0.31) MAPTCYP2C19CYP1A2CYP2C9SMN1; SMN2
SCHEMBL22763820 0.92 MEN1 (0.34) MAPTMEN1KMT2AALDH1A1HPGD
SCHEMBL15908650 0.91 PDK2 (0.33) MAPTKDM4ECYP2C19CYP1A2CYP2C9
SCHEMBL15908625 0.91 MEN1 (0.34) MAPTMEN1KMT2AALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9203033-B2 Nitrogen-containing heterocyclic compounds and organic electronic device comprising the same LG CHEM, LTD. (KR) 2015-12-01 US disclosed
US-9203033-B2 Nitrogen-containing heterocyclic compounds and organic electronic device comprising the same LG CHEM, LTD. (KR) 2015-12-01 US disclosed
US-20140209884-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME LG CHEM LTD. (KR) 2014-07-31 US disclosed
US-20140209884-A1 NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AND ORGANIC ELECTRONIC DEVICE COMPRISING THE SAME LG CHEM LTD. (KR) 2014-07-31 US disclosed