SCHEMBL9883239

SCHEMBL9883239

c1ccc(-c2cc(-c3ccccc3)nc(-c3cccc(-c4ccc5c(c4)c4cccc6c4n5-c4ccccc4C64c5ccccc5-c5ccccc54)c3)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.34
KMT2A Q03164 5/20 0.34
MAPT P10636 5/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
LMNA P02545 3/20 0.34
KDM4E B2RXH2 2/20 0.34
NTSR1 P30989 1/20 0.33
GLA P06280 1/20 0.33
CYP1A2 P05177 2/20 0.31
CYP2C9 P11712 2/20 0.31
CYP2C19 P33261 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CYP3A4 P08684 1/20 0.31
GAA P10253 1/20 0.31
AGTR1 P30556 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
MAPK10 P53779 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
PDK2 Q15119 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15908657 0.98 MAPT (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL15908621 0.96 MEN1 (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL15908629 0.96 MEN1 (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL15908659 0.95 MEN1 (0.38) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL15908625 0.93 MEN1 (0.34) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL24293390 0.92 PDK2 (0.31) MAPTCYP1A2CYP2C9CYP2C19SMN1; SMN2
SCHEMBL15908650 0.92 PDK2 (0.33) MAPTKDM4ECYP1A2CYP2C9CYP2C19
SCHEMBL15908662 0.91 DUSP3 (0.31) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL11926704 0.91
SCHEMBL21867769 0.91 MEN1 (0.35) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9324954-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2016-04-26 US disclosed
US-9324954-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2016-04-26 US disclosed
US-20130240796-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmnH (DE) 2013-09-19 US disclosed
US-20130240796-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES Merck Patent GmnH (DE) 2013-09-19 US disclosed
WO-2012069121-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-05-31 WO disclosed