Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | FAAH | O00519 | 8/20 | 0.38 |
| ▸ | CES1 | P23141 | 6/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15909003 | 1.00 | CES2 (0.38) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL4424795 | 0.87 | CES2 (0.32) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL4424793 | 0.87 | CES2 (0.32) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL6151308 | 0.78 | ODC1 (0.41) | MEN1CYP1A2KMT2A | |
| SCHEMBL6151309 | 0.78 | ODC1 (0.41) | MEN1CYP1A2KMT2A | |
| SCHEMBL308123 | 0.73 | RNPEP (0.31) | — | |
| SCHEMBL308124 | 0.73 | RNPEP (0.31) | — | |
| SCHEMBL7825586 | 0.73 | CES2 (0.43) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL7825590 | 0.73 | CES2 (0.43) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL1706449 | 0.73 | CES2 (0.54) | CES2FAAHCES1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796305-B2 | Carboxy-substituted imidazo[1,2-a]pyridinecarboxamides and their use | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-08-05 | — | — | US | disclosed |