SCHEMBL15909635

SCHEMBL15909635

CC1(C)c2cccc3ccc4cc(-c5ccc(N(c6ccc(C#N)cc6)c6ccc7ccccc7c6)cc5)cc1c4c23

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 6/20 0.36
PDK2 Q15119 1/20 0.34
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
KMT2A Q03164 1/20 0.33
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
PGR P06401 3/20 0.32
SCN9A Q15858 1/20 0.32
AKT1 P31749 2/20 0.31
MYC P01106 1/20 0.31
PARP1 P09874 1/20 0.31
PIM1 P11309 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRG2 P18507 1/20 0.30
GABRB3 P28472 1/20 0.30
GABRA5 P31644 1/20 0.30
GABRA3 P34903 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909625 0.96 HRH3 (0.37) HRH3PDK2LPLLIPGPGR
SCHEMBL15909636 0.95 HRH3 (0.35) HRH3PDK2MEN1NPC1RAB9A
SCHEMBL17849647 0.94 MYC (0.37) HRH3PDK2PGRSCN9AMYC
SCHEMBL15909665 0.94 HRH3 (0.35) HRH3PDK2PGRSCN9AMYC
SCHEMBL17849668 0.94 HRH3 (0.37) HRH3PDK2MEN1NPC1RAB9A
SCHEMBL15429309 0.90 HRH3 (0.33) HRH3
SCHEMBL15909622 0.90 PDK2 (0.40) HRH3PDK2PGR
SCHEMBL15909631 0.89 HRH3 (0.33) HRH3PDK2PGRPIM1
SCHEMBL15909641 0.89 LIMK1 (0.32) HRH3
SCHEMBL17849636 0.89 LPL (0.36) MEN1NPC1RAB9AKMT2ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-9371270-B2 Compound for organic light-emitting device and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-06-21 US disclosed
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209872-A1 COMPOUND, ORGANIC LIGHT EMITTING DEVICE INCLUDING THE COMPOUND, AND FLAT DISPLAY DEVICE INCLUDING THE ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed