SCHEMBL15909735

SCHEMBL15909735

N#Cc1ccc(N(c2ccc(-c3ccccc3)cc2)c2cc3ccc4cccc5ccc(c2)c3c45)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
MYC P01106 1/20 0.39
ALDH1A3 P47895 1/20 0.38
ABCG2 Q9UNQ0 3/20 0.38
KDM4E B2RXH2 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ABCB1 P08183 2/20 0.37
CYP1A1 P04798 1/20 0.37
CYP1B1 Q16678 1/20 0.37
HRH3 Q9Y5N1 3/20 0.36
CYP11B2 P19099 1/20 0.36
KAT6A Q92794 1/20 0.36
TSHR P16473 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
PTGDR2 Q9Y5Y4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16272131 0.96 KDM4E (0.40) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15909741 0.93 KDM4E (0.40) ABCG2KDM4ETDP1CYP1A1CYP1B1
SCHEMBL15731011 0.91 KDM4E (0.43) KDM4ETDP1CYP1A1CYP1B1HRH3
SCHEMBL20243301 0.90 MYC (0.39) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15909777 0.90 MYC (0.44) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15731019 0.88 CYP1A2 (0.41) KDM4ETDP1CYP1A1CYP1B1TSHR
SCHEMBL16271365 0.88 CYP1A2 (0.41) KDM4ETDP1CYP1A1CYP1B1TSHR
SCHEMBL6844368 0.86 CYP1A2 (0.39) KDM4ETDP1CYP1A1CYP1B1TSHR
SCHEMBL15909783 0.86 HRH3 (0.43) GABRA1GABRG2GABRB3GABRA5GABRA3
SCHEMBL15909743 0.86 CYP11B2 (0.59) ABCG2CYP11B2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed