SCHEMBL15909752

SCHEMBL15909752

N#Cc1ccc(N(c2cccnc2)c2cc3ccc4cc(-c5ccccc5)cc5ccc(c2)c3c45)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 6/20 0.48
CYP11B1 P15538 5/20 0.48
CYP17A1 P05093 2/20 0.48
CYP19A1 P11511 6/20 0.39
ABCG2 Q9UNQ0 2/20 0.39
ADORA2A P29274 3/20 0.38
ADORA1 P30542 3/20 0.38
ABCB1 P08183 1/20 0.38
ABCC1 P33527 1/20 0.38
GABRA1 P14867 1/20 0.37
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
NPY5R Q15761 1/20 0.37
CYP3A4 P08684 1/20 0.37
ADORA2B P29275 1/20 0.36
KDM4E B2RXH2 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15909769 0.96 CYP11B2 (0.52) CYP11B2CYP11B1CYP17A1CYP19A1ABCG2
SCHEMBL15909781 0.96 CYP11B2 (0.52) CYP11B2CYP11B1CYP17A1CYP19A1ABCG2
SCHEMBL15909780 0.94 CYP11B2 (0.54) CYP11B2CYP11B1CYP17A1CYP19A1ABCG2
SCHEMBL15909775 0.91 CYP11B2 (0.61) CYP11B2CYP11B1CYP17A1CYP19A1ABCG2
SCHEMBL15909754 0.89 CYP19A1 (0.47) CYP11B2CYP11B1CYP17A1CYP19A1NPY5R
SCHEMBL20243301 0.89 MYC (0.39) CYP11B2CYP11B1CYP17A1CYP19A1ABCG2
SCHEMBL15909782 0.89 CYP11B2 (0.62) CYP11B2CYP11B1CYP17A1CYP19A1ABCG2
SCHEMBL15909779 0.86 CYP11B2 (0.47) CYP11B2CYP11B1CYP17A1CYP19A1KDM4E
SCHEMBL15909763 0.86 CYP11B2 (0.47) CYP11B2CYP11B1CYP17A1CYP19A1KDM4E
SCHEMBL15909788 0.85 CYP11B2 (0.41) CYP11B2CYP11B1CYP17A1CYP19A1ABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-9997713-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-12 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed
US-20140209875-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-31 US disclosed