SCHEMBL15910550

SCHEMBL15910550

C=C(C)C(=O)OCCCCOc1ccccc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.54
POLB P06746 1/20 0.52
APEX1 P27695 1/20 0.52
HTT P42858 1/20 0.52
TSHR P16473 2/20 0.50
ALDH1A1 P00352 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.46
LMNA P02545 3/20 0.45
MAPK1 P28482 2/20 0.45
USP2 O75604 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
MAPT P10636 1/20 0.43
CYP2C19 P33261 2/20 0.43
CYP2D6 P10635 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
MCL1 Q07820 1/20 0.43
NR2F2 P24468 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15911011 0.98 TDP1 (0.55) TDP1POLBAPEX1HTTTSHR
SCHEMBL15910936 0.98 TDP1 (0.55) TDP1POLBAPEX1HTTTSHR
SCHEMBL13328823 0.97 TDP1 (0.54) TDP1POLBAPEX1HTTTSHR
SCHEMBL31426927 0.92 TDP1 (0.51) TDP1POLBAPEX1HTTALDH1A1
SCHEMBL649097 0.92 TDP1 (0.51) TDP1POLBAPEX1HTTALDH1A1
SCHEMBL15910793 0.85 LMNA (0.61) TDP1POLBAPEX1HTTTSHR
SCHEMBL16273360 0.84 TDP1 (0.46) TDP1HTTALDH1A1LMNAMEN1
SCHEMBL11341216 0.84 TDP1 (0.46) TDP1POLBAPEX1HTTTSHR
SCHEMBL29035661 0.84 TDP1 (0.55) TDP1POLBAPEX1HTTTSHR
SCHEMBL15910755 0.84 LMNA (0.60) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2762506-B1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORP (JP) 2022-09-07 EP disclosed
US-9708424-B2 (Meth)acryloyl-terminated polyisobutylene polymer, method for producing the same, and active energy ray-curable composition KANEKA CORPORATION (JP) 2017-07-18 US disclosed
US-20170051093-A1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING THE SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORP (JP) 2017-02-23 US disclosed
US-9512247-B2 (Meth)acryloyl-terminated polyisobutylene polymer, method for producing the same, and active energy ray-curable composition KANEKA CORPORATION (JP) 2016-12-06 US disclosed
US-20140243444-A1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING THE SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORPORATION (JP) 2014-08-28 US disclosed
EP-2762506-A1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION Kaneka Corporation (JP) 2014-08-06 EP disclosed
CN-103827158-A (meth)acryloyl-terminated polyisobutylene polymer, method for producing same, and active energy ray-curable composition KANEKA CORP 2014-05-28 CN disclosed