Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA6 | P23280 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3045824 | 0.88 | ALDH1A1 (0.49) | ALDH1A1PTPN1PTPRCTDP1SLC6A2 | |
| SCHEMBL23876180 | 0.88 | KMT2A (0.50) | LMNAALDH1A1PTPN1PTPRCTDP1 | |
| SCHEMBL228601 | 0.88 | NR4A2 (0.51) | LMNAALDH1A1PTPN1PTPRCTDP1 | |
| SCHEMBL23876186 | 0.88 | NPC1 (0.49) | LMNAALDH1A1PTPN1PTPRCTDP1 | |
| SCHEMBL13313606 | 0.86 | MAOB (0.59) | LMNAALDH1A1SLC6A2SLC6A3L3MBTL1 | |
| SCHEMBL11625164 | 0.84 | ALDH1A1 (0.49) | LMNAALDH1A1PTPN1PTPRCTDP1 | |
| SCHEMBL24773109 | 0.84 | POLB (0.52) | LMNAALDH1A1PTPN1CHRM2CHRM4 | |
| SCHEMBL17472474 | 0.83 | ALDH1A1 (0.47) | LMNAALDH1A1CHRM2CHRM4CHRM1 | |
| SCHEMBL4679715 | 0.82 | ALDH1A1 (0.46) | ALDH1A1PTPN1PTPRCTDP1SLC6A2 | |
| SCHEMBL25300422 | 0.82 | PTPN1 (0.46) | ALDH1A1PTPN1PTPRCTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10835520-B2 | Phenyl derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2020-11-17 | — | — | US | disclosed |
| US-20190030010-A1 | PHENYL DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2019-01-31 | — | — | US | disclosed |
| US-10117861-B2 | Phenyl derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-11-06 | — | — | US | disclosed |
| EP-3150577-B1 | PHENYL DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2018-08-29 | — | — | EP | disclosed |
| CN-105189454-B | Phenyl derivatives | 小野药品工业株式会社 | 2018-07-13 | — | — | CN | disclosed |
| EP-2980072-B1 | PHENYL DERIVATIVE | ONO PHARMACEUTICAL CO (JP) | 2018-04-25 | — | — | EP | disclosed |
| US-20180042908-A1 | PHENYL DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2018-02-15 | — | — | US | disclosed |
| US-9820980-B2 | Phenyl derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-11-21 | — | — | US | disclosed |
| US-9676719-B2 | Phenyl derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-06-13 | — | — | US | disclosed |
| EP-3150577-A1 | PHENYL DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2017-04-05 | — | — | EP | disclosed |
| US-20160213660-A1 | PHENYL DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-07-28 | — | — | US | disclosed |
| US-9340499-B2 | Phenyl derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-05-17 | — | — | US | disclosed |
| US-20160039757-A1 | PHENYL DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2016-02-11 | — | — | US | disclosed |
| EP-2980072-A1 | PHENYL DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2016-02-03 | — | — | EP | disclosed |
| CN-105189454-A | Phenyl derivative | ONO PHARMACEUTICAL CO | 2015-12-23 | — | — | CN | disclosed |
| US-20150126486-A1 | PHENYL DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-05-07 | — | — | US | disclosed |
| US-8975409-B2 | Phenyl derivative | ONO PHARMACEUTICAL CO., LTD. (JP) | 2015-03-10 | — | — | US | disclosed |
| US-20140235611-A1 | PHENYL DERIVATIVE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2014-08-21 | — | — | US | disclosed |
| EP-2762466-A1 | PHENYL DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2014-08-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10117861-B2 | Phenyl derivative | S1PR2, S1PR1, S1PR3 | LMNA 1664/4885ALDH1A1 1254/4885CA12 4824/4885 |
| US-20150126486-A1 | PHENYL DERIVATIVE | S1PR2, S1PR1, S1PR3 | LMNA 1797/4885ALDH1A1 1253/4885CA12 4811/4885 |
| US-20180042908-A1 | PHENYL DERIVATIVE | S1PR2, S1PR1, S1PR3 | LMNA 1664/4885ALDH1A1 1254/4885CA12 4824/4885 |
| US-20190030010-A1 | PHENYL DERIVATIVE | S1PR2, S1PR1, S1PR3 | LMNA 1664/4885ALDH1A1 1254/4885CA12 4824/4885 |
| US-20160213660-A1 | PHENYL DERIVATIVE | S1PR2, S1PR1, S1PR3 | LMNA 1664/4885ALDH1A1 1254/4885CA12 4824/4885 |
| US-20140235611-A1 | PHENYL DERIVATIVE | S1PR2, S1PR1, S1PR3 | LMNA 1797/4885ALDH1A1 1253/4885CA12 4811/4885 |
| US-10835520-B2 | Phenyl derivative | S1PR2, S1PR1, S1PR3 | LMNA 1664/4885ALDH1A1 1254/4885CA12 4824/4885 |
| US-20160039757-A1 | PHENYL DERIVATIVE | S1PR2, S1PR1, S1PR5 | LMNA 2931/4885ALDH1A1 2273/4885CA12 4559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.