Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 6/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CCR2 | P41597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911644 | 0.94 | F10 (0.68) | F10SIGMAR1DRD4MCHR1MAPT | |
| SCHEMBL1674963 | 0.89 | F10 (0.79) | F10DRD4CCR2 | |
| SCHEMBL15911708 | 0.89 | F10 (0.78) | F10SIGMAR1DRD4MCHR1 | |
| SCHEMBL15911647 | 0.88 | F10 (0.65) | F10SIGMAR1DRD4MCHR1CCR2 | |
| SCHEMBL15911349 | 0.88 | F10 (0.65) | F10SIGMAR1DRD4MCHR1MAPT | |
| SCHEMBL15911489 | 0.87 | F10 (0.68) | F10SIGMAR1DRD4MCHR1MAPT | |
| SCHEMBL15911630 | 0.85 | F10 (0.63) | F10SIGMAR1DRD4PLA2G2AMCHR1 | |
| SCHEMBL1675042 | 0.82 | F10 (0.87) | F10DRD4CCR2 | |
| SCHEMBL15911525 | 0.82 | F10 (0.65) | F10SIGMAR1DRD4 | |
| SCHEMBL15911445 | 0.82 | F10 (0.69) | F10SIGMAR1DRD4MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451185-B1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2014-08-06 | — | — | EP | claimed |