Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.63 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911644 | 0.91 | F10 (0.68) | F10DRD4MCHR1SIGMAR1 | |
| SCHEMBL1675121 | 0.90 | F10 (0.78) | F10DRD4 | |
| SCHEMBL15911647 | 0.88 | F10 (0.65) | F10DRD4MCHR1SIGMAR1 | |
| SCHEMBL15911349 | 0.88 | F10 (0.65) | F10DRD4MCHR1SIGMAR1TP53 | |
| SCHEMBL15911708 | 0.87 | F10 (0.78) | F10DRD4MCHR1KMT2ASIGMAR1 | |
| SCHEMBL15911489 | 0.86 | F10 (0.68) | F10DRD4MCHR1SIGMAR1 | |
| SCHEMBL15911461 | 0.85 | F10 (0.63) | F10DRD4MCHR1SIGMAR1PLA2G2A | |
| SCHEMBL15911591 | 0.81 | F10 (0.63) | F10DRD4MCHR1SIGMAR1 | |
| SCHEMBL1675042 | 0.81 | F10 (0.87) | F10DRD4 | |
| SCHEMBL15911445 | 0.80 | F10 (0.69) | F10DRD4MCHR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451185-B1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2014-08-06 | — | — | EP | claimed |