Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 12/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GPR6 | P46095 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786933 | 0.95 | AVPR1B (0.44) | AVPR1BHCRTR1HCRTR2KMT2ACYP3A4 | |
| SCHEMBL1786064 | 0.94 | AVPR1B (0.44) | AVPR1BHCRTR1HCRTR2KMT2ACYP3A4 | |
| SCHEMBL15911611 | 0.94 | AVPR1B (0.41) | AVPR1BHCRTR1HCRTR2KMT2ACYP3A4 | |
| SCHEMBL15911642 | 0.94 | AVPR1B (0.41) | AVPR1BHCRTR1HCRTR2KMT2ACYP3A4 | |
| SCHEMBL15911619 | 0.94 | AVPR1B (0.48) | AVPR1BHCRTR1HCRTR2KMT2ACYP3A4 | |
| SCHEMBL1785523 | 0.92 | AVPR1B (0.44) | AVPR1BHCRTR1HCRTR2KMT2ACYP3A4 | |
| SCHEMBL15911688 | 0.92 | AVPR1B (0.47) | AVPR1BHCRTR1HCRTR2CYP3A4GAA | |
| SCHEMBL1787797 | 0.91 | AVPR1B (0.43) | AVPR1BHCRTR1HCRTR2KMT2ACYP3A4 | |
| SCHEMBL15911612 | 0.91 | AVPR1B (0.51) | AVPR1BHCRTR1HCRTR2CYP3A4GPR6 | |
| SCHEMBL1786579 | 0.89 | AVPR1B (0.43) | AVPR1BHCRTR1HCRTR2KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815868-B2 | Substituted oxindole derivatives and their use as vasopressin receptor ligands | ABBOTT GMBH & CO. KG (DE) | 2014-08-26 | — | — | US | claimed |
| EP-2114923-B1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | ABBOTT GMBH & CO KG (DE) | 2014-08-06 | — | — | EP | claimed |
| EP-2114923-B1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | ABBOTT GMBH & CO KG (DE) | 2014-08-06 | — | — | EP | disclosed |