Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 12/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911611 | 0.98 | AVPR1B (0.41) | AVPR1BKMT2AGPR6CYP3A4HCRTR1 | |
| SCHEMBL1785632 | 0.95 | AVPR1B (0.42) | AVPR1BKMT2AGPR6CYP3A4HCRTR1 | |
| SCHEMBL1786579 | 0.94 | AVPR1B (0.43) | AVPR1BKMT2AGPR6CYP3A4HCRTR1 | |
| SCHEMBL15911697 | 0.94 | AVPR1B (0.46) | AVPR1BGPR6CYP3A4 | |
| SCHEMBL15911545 | 0.94 | AVPR1B (0.43) | AVPR1BKMT2AGPR6CYP3A4HCRTR1 | |
| SCHEMBL1786116 | 0.93 | AVPR1B (0.43) | AVPR1BKMT2AGPR6CYP3A4HCRTR1 | |
| SCHEMBL1784956 | 0.93 | AVPR1B (0.42) | AVPR1BKMT2AGPR6CYP3A4HCRTR1 | |
| SCHEMBL15911661 | 0.92 | AVPR1B (0.46) | AVPR1BGPR6CYP3A4HCRTR1HCRTR2 | |
| SCHEMBL16053556 | 0.92 | AVPR1B (0.42) | AVPR1BKMT2AGPR6CYP3A4HCRTR1 | |
| SCHEMBL1785366 | 0.92 | AVPR1B (0.43) | AVPR1BKMT2AGPR6CYP3A4HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114923-B1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | ABBOTT GMBH & CO KG (DE) | 2014-08-06 | — | — | EP | claimed |
| EP-2114923-B1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | ABBOTT GMBH & CO KG (DE) | 2014-08-06 | — | — | EP | disclosed |