Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911269 | 0.89 | F10 (0.58) | F10LMNACYP3A4CYP2D6KMT2A | |
| SCHEMBL1675311 | 0.87 | F10 (0.59) | F10LMNADRD4ALDH1A1POLB | |
| SCHEMBL15911583 | 0.86 | F10 (0.66) | F10CHRM4LMNAKMT2ADRD4 | |
| SCHEMBL15911496 | 0.83 | F10 (0.51) | F10LMNA | |
| SCHEMBL1675113 | 0.80 | F10 (0.74) | F10DRD4 | |
| SCHEMBL15911648 | 0.77 | F10 (0.47) | F10 | |
| SCHEMBL15911366 | 0.76 | F10 (0.78) | F10 | |
| SCHEMBL15911708 | 0.74 | F10 (0.78) | F10KMT2ADRD4 | |
| SCHEMBL15911640 | 0.74 | F10 (0.53) | F10DRD4 | |
| SCHEMBL8354384 | 0.73 | F10 (0.55) | F10LMNAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451185-B1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2014-08-06 | — | — | EP | claimed |