Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 15/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | GPR6 | P46095 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15911698 | 0.98 | AVPR1B (0.46) | AVPR1BCYP3A4GPR6ALDH1A1CCR6 | |
| SCHEMBL1787086 | 0.95 | AVPR1B (0.47) | AVPR1BCYP3A4GPR6ALDH1A1 | |
| SCHEMBL1786060 | 0.95 | AVPR1B (0.48) | AVPR1BCYP3A4GPR6ALDH1A1 | |
| SCHEMBL15911619 | 0.94 | AVPR1B (0.48) | AVPR1BCYP3A4GPR6CCR6 | |
| SCHEMBL15911642 | 0.94 | AVPR1B (0.41) | AVPR1BCYP3A4GPR6 | |
| SCHEMBL1786572 | 0.94 | AVPR1B (0.48) | AVPR1BCYP3A4GPR6CCR6 | |
| SCHEMBL1786044 | 0.93 | AVPR1B (0.47) | AVPR1BCYP3A4GPR6ALDH1A1CCR6 | |
| SCHEMBL16053377 | 0.92 | AVPR1B (0.47) | AVPR1BCYP3A4GPR6ALDH1A1CCR6 | |
| SCHEMBL16053379 | 0.92 | AVPR1B (0.47) | AVPR1BCYP3A4GPR6ALDH1A1CCR6 | |
| SCHEMBL1787061 | 0.92 | AVPR1B (0.48) | AVPR1BCYP3A4GPR6ALDH1A1CCR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8815868-B2 | Substituted oxindole derivatives and their use as vasopressin receptor ligands | ABBOTT GMBH & CO. KG (DE) | 2014-08-26 | — | — | US | claimed |
| EP-2114923-B1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | ABBOTT GMBH & CO KG (DE) | 2014-08-06 | — | — | EP | claimed |
| EP-2114923-B1 | SUBSTITUTED OXINDOLE DERIVATIVES AND THEIR USE AS VASOPRESSIN RECEPTOR LIGANDS | ABBOTT GMBH & CO KG (DE) | 2014-08-06 | — | — | EP | disclosed |