SCHEMBL15912152

SCHEMBL15912152

O=C(CS(=O)(=O)Oc1ccccc1)Oc1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
CA1 P00915 3/20 0.39
CA2 P00918 3/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39
CA13 Q8N1Q1 1/20 0.39
MEN1 O00255 2/20 0.37
CA9 Q16790 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
STS P08842 2/20 0.33
HSD11B1 P28845 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SENP8 Q96LD8 1/20 0.33
SENP7 Q9BQF6 1/20 0.33
SENP6 Q9GZR1 1/20 0.33
YAP1 P46937 1/20 0.33
TEAD4 Q15561 1/20 0.33
TEAD2 Q15562 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15801005 0.84 KMT2A (0.52) KMT2ACA1CA2MEN1CA9
SCHEMBL15800974 0.81 FAAH (0.45) KMT2ACA1CA2MEN1CA9
SCHEMBL15800986 0.81 KMT2A (0.42) KMT2ACA1CA2CA12CA7
SCHEMBL8941449 0.79 KMT2A (0.50) KMT2ACA1CA2CA12CA7
SCHEMBL15800951 0.76 GAA (0.52) KMT2AMEN1SMN1; SMN2STSHSD11B1
SCHEMBL15912191 0.75 CA1 (0.33) KMT2ACA1CA2MEN1CA9
SCHEMBL28814863 0.75 KMT2A (0.53) KMT2ACA1CA2MEN1CA9
SCHEMBL15800954 0.75 TSHR (0.51) KMT2ACA1CA2MEN1CA9
SCHEMBL27582686 0.75 KMT2A (0.57) KMT2ACA1CA2CA12MEN1
SCHEMBL29289426 0.73 KMT2A (0.55) KMT2ACA1CA2CA12MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140212770-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ulbe industries, Ltd. (JP) 2014-07-31 US disclosed
US-20140212770-A1 NONAQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL ELEMENT USING SAME Ulbe industries, Ltd. (JP) 2014-07-31 US disclosed