SCHEMBL1591264

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12328430	0.84	MEN1 (0.74)	MEN1KMT2APLK1PDGFRB
	SCHEMBL2421827	0.78	PIM1 (0.74)	MAPTMEN1KMT2AHPGDPIM1
	SCHEMBL2421824	0.78	PIM1 (0.74)	MAPTMEN1KMT2AHPGDPIM1
	SCHEMBL1591188	0.78	MAPT (0.72)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL885537	0.76	MEN1 (0.60)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL10090249	0.76	MEN1 (0.60)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL2065345	0.76	MEN1 (0.60)	MAPTALDH1A1MEN1KMT2APOLB
	SCHEMBL14521224	0.76	PDGFRB (0.54)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL22095992	0.75	MAPT (1.00)	MAPTALDH1A1KDM4EMEN1KMT2A
	SCHEMBL14521150	0.74	MEN1 (0.53)	MAPTALDH1A1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.