SCHEMBL159133

SCHEMBL159133

O=P(O)(O)NCl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10414012 1.00
SCHEMBL28242531 0.78
SCHEMBL16554046 0.75
SCHEMBL3153854 0.70
Phosphoric Acid SCHEMBL27699326 0.70
Phosphoric Acid SCHEMBL15312963 0.68 CA2 (0.50)
Phosphoric Acid SCHEMBL2092954 0.68 CA2 (0.50)
Phosphoric Acid SCHEMBL107716 0.68
Phosphoric Acid SCHEMBL2815522 0.68 CA2 (0.50)
Phosphoric Acid SCHEMBL6244258 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4224 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12378267-B2 Synthesis of FMOC-protected morpholino monomers and oligomers ENTRADA THERAPEUTICS, INC. (US) 2025-08-05 US claimed
US-20240238282-A1 METHODS OF TREATING CANCER AND ISCHEMIA DISEASES BY INHIBITION AND INTERVENTION OF ATR PROLYL ISOMERIZATION THE UNIVERSITY OF TOLEDO (US) 2024-07-18 US claimed
US-12012427-B2 Synthesis of Fmoc-protected morpholino monomers and their use in the synthesis of morpholino oligomer INDIAN ASSOCIATION FOR THE CULTIVATION OF SCIENCE (IN) 2024-06-18 US claimed
CN-114957364-B Iodine base, preparation method thereof and constructed amphiphilic nucleic acid 湖南大学 2024-01-23 CN claimed
US-20230097585-A1 SYNTHESIS OF FMOC-PROTECTED MORPHOLINO MONOMERS AND OLIGOMERS ENTRADA THERAPEUTICS, INC. 2023-03-30 US claimed
CN-113754694-B Method for synthesizing Reidesvir by asymmetric catalysis of non-protecting group nucleoside 上海交通大学 2022-10-25 CN claimed
CN-113747947-A Combination therapy 沙塔克实验室有限公司 2021-12-03 CN claimed
CN-113727722-A Bacterial membrane preparation 伊夫罗生物科学公司 2021-11-30 CN claimed
CN-113727734-A Ligand-drug conjugates comprising a linker having a tris structure 乐高化学生物科学股份有限公司 2021-11-30 CN claimed
CN-113599533-A Antibody-drug conjugates comprising branched linkers and methods related thereto 乐高化学生物科学股份有限公司 2021-11-05 CN claimed
US-8846681-B2 Pyrimidyl cyclopentanes as AKT protein kinase inhibitors ARRAY BIOPHARMA, INC. (US) 2014-09-30 US claimed
US-20130261104-A1 METHODS OF USE OF DIAZACARBAZOLES FOR TREATING CANCER GENENTECH, INC. (US) 2013-10-03 US claimed
EP-2402325-A2 Hydroxylated and methoxylated cyclopenta[d]pyrimidines as AKT protein kinase inhibitors Array Biopharma, Inc. (US) 2012-01-04 EP claimed
US-8076476-B2 Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits AVI BIOPHARMA, INC. (US) 2011-12-13 US claimed
US-20110245230-A1 PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS ARRAY BIOPHARMA INC. (US) 2011-10-06 US claimed
EP-2207779-A1 METHOD OF SYNTHESIS OF MORPHOLINO OLIGOMERS Avi Biopharma, Inc. (US) 2010-07-21 EP claimed
WO-2009064471-A1 METHOD OF SYNTHESIS OF MORPHOLINO OLIGOMERS AVI BIOPHARMA, INC. (US) 2009-05-22 WO claimed
US-20090131624-A1 SYNTHESIS OF MORPHOLINO OLIGOMERS USING DOUBLY PROTECTED GUANINE MORPHOLINO SUBUNITS AVI BIOPHARMA, INC. (US) 2009-05-21 US claimed
EP-1468007-A2 PSEUDONUCLEOTIDE COMPRISING AN INTERCALATOR Human Genetic Signatures PTY Ltd. (AU) 2004-10-20 EP claimed
WO-2003051901-A2 PSEUDONUCLEOTIDE COMPRISING AN INTERCALATOR HUMAN GENETIC SIGNATURES PTY LTD (AU) 2003-06-26 WO claimed