⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28563909 | 0.74 | — | — | |
| SCHEMBL11469697 | 0.74 | — | — | |
| SCHEMBL29965421 | 0.69 | — | — | |
| Propane SCHEMBL7454469 | 0.65 | — | — | |
| SCHEMBL1338841 | 0.64 | — | — | |
| SCHEMBL2933911 | 0.63 | FDPS (0.31) | — | |
| SCHEMBL1218125 | 0.63 | — | — | |
| SCHEMBL14498521 | 0.61 | — | — | |
| SCHEMBL14498522 | 0.61 | — | — | |
| SCHEMBL1345524 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130172587-A1 | Process for the Preparation of Fluticasone Propionate | GENERICS [UK] LIMITED (GB) | 2013-07-04 | — | — | US | claimed |
| US-8344168-B2 | Process for the preparation of fluticasone propionate | GENERICS (UK) LIMITED (GB) | 2013-01-01 | — | — | US | claimed |
| EP-2044099-B1 | PROCESS FOR THE PREPARATION OF S-FLUOROMETHYL-6 ,9 -DIFLUORO-11 -HYDROXY-16 -METHYL-17 -PROPIONYLOXY-3-OXO-ANDROSTA-1,4-DIENE-17 -CARBOTHIOATE AND INTERMEDIATES | GENERICS UK LTD (GB) | 2012-05-23 | — | — | EP | claimed |
| EP-2402360-A1 | Process for the preparation of S-fluoromethyl-6,9-difluoro-11-hydroxy-16-methyl-17-propionyloxy-3-oxo-androsta-1,4-diene-17-carbothioate and intermediates | Generics (UK) Limited (GB) | 2012-01-04 | — | — | EP | claimed |
| EP-2402361-A1 | Process for the preparation of S-fluoromethyl-6,9-difluoro-11-hydroxy-16-methyl-17-propionyloxy-3-oxo-androsta-1,4-diene-17-carbothioate and intermediates | Generics (UK) Limited (GB) | 2012-01-04 | — | — | EP | claimed |
| US-20090177001-A1 | NOVEL PROCESS AND INTERMEDIATES | GENERICS [UK] LIMITED (INCORPORATED IN THE UNITED KINGDOM] (GB) | 2009-07-09 | — | — | US | claimed |
| EP-2044099-A2 | PROCESS FOR THE PREPARATION OF S-FLUOROMETHYL-6 ,9 -DIFLUORO-11 -HYDROXY-16 -METHYL-17 -PROPIONYLOXY-3-OXO-ANDROSTA-1,4-DIENE-17 -CARBOTHIOATE AND INTERMEDIATES | Merck Generics (UK) Limited (GB) | 2009-04-08 | — | — | EP | claimed |
| WO-2007144668-A2 | PROCESS FOR THE PREPARATION OF S-FLUOROMETHYL-6, 9 -DIFLUORO-11 -HYDROXY-16 -METHYL-17-PROPIONYLOXY-3-OXO-ANDROSTA-1,4-DIENE-17 -CARBOTHIOATE AND INTERMEDIATES | GENERICS [UK] LIMITED (GB) | 2007-12-21 | — | — | WO | claimed |
| US-20060116359-A1 | 17.Beta-(alpha-hydroxy)-esters of androstanes as intermediates for the preparation of 17.beta-fluorinated-androstane esters | FARMABIOS S.P.A. (IT) | 2006-06-01 | — | — | US | claimed |
| EP-1575983-A1 | 17.BETA-[ALPHA-HYDROXY]-ESTERS OF ANDROSTANES AS INTERMEDIATES FOR THE PREPARATION OF 17.BETA.-FLUORINATED-ANDROSTANE ESTERS | Farmabios S.p.A. (IT) | 2005-09-21 | — | — | EP | claimed |
| WO-2004052912-A1 | 17.BETA- (ALPHA-HYDROXY) -ESTERS OF ANDROSTANES AS INTERMEDIATES FOR THE PREPARATION FOR THE PREPARATION OF 17.BETA.-FLUORINATED-ANDROSTANE ESTERS | FARMABIOS S.P.A. (IT) | 2004-06-24 | — | — | WO | claimed |
| EP-1187847-B1 | STREPTOGRAMIN DERIVATIVES, PREPARATION AND COMPOSITIONS CONTAINING THEM | AVENTIS PHARMA SA (FR) | 2003-12-03 | — | — | EP | claimed |
| US-20030149004-A1 | Streptogramin derivatives, their preparation and compositions containing them | AVENTIS PHARMA S.A. | 2003-08-07 | — | — | US | claimed |
| US-6569854-B1 | Virginamycins | AVENTIS PHARMA S.A. (FR) | 2003-05-27 | — | — | US | claimed |
| US-6541451-B1 | Bactericides; microorganisms | AVENTIS PHARMA S.A. (FR) | 2003-04-01 | — | — | US | claimed |
| US-20240102156-A1 | METHODS FOR PROVIDING A PRECURSOR MIXTURE TO A REACTION CHAMBER | ASM IP HOLDING B.V. (NL) | 2024-03-28 | — | — | US | disclosed |
| CN-117660932-A | Method for providing a precursor mixture to a reaction chamber | ASM IP私人控股有限公司 | 2024-03-08 | — | — | CN | disclosed |
| US-5451601-A | Perhydroisoindole derivatives and pharmaceutical compositions containing them | RHONE-POULENC RORER S.A. (FR) | 1995-09-19 | — | — | US | disclosed |
| EP-0433759-A1 | 4-Substituted alkyl carbapenem antibiotics | Bristol-Myers Squibb Company (US) | 1991-06-26 | — | — | EP | disclosed |
| US-4544504-A | UNSATURATED ACYL FLUORIDES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1985-10-01 | — | — | US | disclosed |