SCHEMBL15914120

SCHEMBL15914120

CCCN1CCN(CCc2c(-c3ccc(OC)cc3)nc3ccc(-c4ccc(N(C)C)cc4)cn23)CC1

nearest known ligand 0.53

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ SLC2A1 P11166 15/20 0.53
▸ SLC2A2 P11168 2/20 0.50
▸ TSPO P30536 1/20 0.44
▸ APP P05067 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12818818 0.92 SLC2A1 (0.63) SLC2A1SLC2A2
SCHEMBL15914119 0.83 SLC2A1 (0.44) SLC2A1SLC2A2TSPOAPP
SCHEMBL12819214 0.81 SLC2A1 (0.59) SLC2A1
SCHEMBL15914477 0.80 SLC2A1 (0.61) SLC2A1SLC2A2
SCHEMBL12818496 0.77 SLC2A1 (0.58) SLC2A1SLC2A2
SCHEMBL15914576 0.76 SLC2A1 (0.49) SLC2A1SLC2A2
SCHEMBL15914748 0.76 SLC2A1 (0.49) SLC2A1SLC2A2
SCHEMBL15915210 0.75 SLC2A1 (0.49) SLC2A1SLC2A2TSPO
SCHEMBL15914229 0.74 SLC2A2 (0.45) SLC2A1SLC2A2
SCHEMBL15914948 0.73 SLC2A1 (0.65) SLC2A1SLC2A2TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140221354-A1 IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY EMBLEM TECHNOLOGY TRANSFER GMBH (DE) 2014-08-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140221354-A1 IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY HIF1A, HIF1AN, EGLN3 SLC2A1 1235/4885SLC2A2 1610/4885TSPO 688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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