Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 3/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15914401 | 1.00 | CYP2D6 (0.36) | CYP2D6KDM4ECYP1A2PDE4ASMN1; SMN2 | |
| SCHEMBL15914400 | 1.00 | CYP2D6 (0.36) | CYP2D6KDM4ECYP1A2PDE4ASMN1; SMN2 | |
| SCHEMBL15914402 | 1.00 | CYP2D6 (0.36) | CYP2D6KDM4ECYP1A2PDE4ASMN1; SMN2 | |
| SCHEMBL15914361 | 0.83 | LTA4H (0.40) | CYP2D6MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL15914362 | 0.83 | LTA4H (0.40) | CYP2D6MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL14672244 | 0.83 | LTA4H (0.40) | CYP2D6MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL15914360 | 0.83 | LTA4H (0.40) | CYP2D6MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL15751312 | 0.82 | LTA4H (0.39) | CYP2D6MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL15751313 | 0.81 | LTA4H (0.35) | CYP2D6KDM4ECYP1A2PDE4ASMN1; SMN2 | |
| SCHEMBL15751314 | 0.81 | LTA4H (0.35) | CYP2D6KDM4ECYP1A2PDE4ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115079-B2 | NDM inhibitor | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140221330-A1 | NDM INHIBITOR | MEIJI SEIKA PHARMA CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221330-A1 | NDM INHIBITOR | MGAM, NQO1, NQO2 | CYP2D6 810/4885KDM4E 1682/4885CYP1A2 1167/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.