Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 11/20 | 0.43 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 2/20 | 0.40 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12819049 | 0.93 | SLC2A1 (0.52) | SLC2A1CHKAALDH1A1KDM4E | |
| SCHEMBL15914584 | 0.91 | SLC2A1 (0.43) | SLC2A1SLC2A2CHKAALDH1A1KDM4E | |
| SCHEMBL15914576 | 0.87 | SLC2A1 (0.49) | SLC2A1SLC2A2CHKA | |
| SCHEMBL15914748 | 0.87 | SLC2A1 (0.49) | SLC2A1SLC2A2CHKA | |
| SCHEMBL15914562 | 0.85 | SLC2A1 (0.43) | SLC2A1SLC2A2CHKAKDM4EHPGD | |
| SCHEMBL15914730 | 0.84 | SLC2A1 (0.44) | SLC2A1SLC2A2CHKAALDH1A1KDM4E | |
| SCHEMBL12818783 | 0.83 | SLC2A1 (0.52) | SLC2A1SLC2A2CHKA | |
| SCHEMBL12818589 | 0.82 | SLC2A1 (0.64) | SLC2A1SLC2A2KDM4E | |
| SCHEMBL15914419 | 0.82 | SLC2A1 (0.41) | SLC2A1SLC2A2CHKAMTNR1AMTNR1B | |
| SCHEMBL15914902 | 0.82 | SLC2A1 (0.42) | SLC2A1SLC2A2CHKAMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221354-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY | EMBLEM TECHNOLOGY TRANSFER GMBH (DE) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221354-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS FOR USE IN THERAPY | HIF1A, HIF1AN, EGLN3 | SLC2A1 1235/4885SLC2A2 1610/4885CHKA 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.