SCHEMBL15914955

SCHEMBL15914955

NC(=O)CCCCCOC1CCCCO1

nearest known ligand 0.56

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
KDM4C Q9H3R0 1/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
ALOX12 P18054 1/20 0.36
POLB P06746 2/20 0.34
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SPHK1 Q9NYA1 2/20 0.33
ICAM1 P05362 1/20 0.33
SELE P16581 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15914379 1.00 MEN1 (0.56) MEN1KMT2AKDM4CTP53HPGD
SCHEMBL10704936 1.00 MEN1 (0.56) MEN1KMT2AKDM4CTP53HPGD
SCHEMBL9731947 1.00 MEN1 (0.56) MEN1KMT2AKDM4CTP53HPGD
SCHEMBL15914347 0.98 KMT2A (0.53) MEN1KMT2AKDM4CTP53HPGD
SCHEMBL20764819 0.95 MEN1 (0.53) MEN1KMT2AKDM4CHPGDPOLB
SCHEMBL9788 0.95 MEN1 (0.53) MEN1KMT2AKDM4CHPGDPOLB
SCHEMBL11539684 0.90 MEN1 (0.48) MEN1KMT2AKDM4CPOLBLMNA
SCHEMBL18350198 0.89 MEN1 (0.57) MEN1KMT2AKDM4CTP53HPGD
SCHEMBL4100095 0.87 MEN1 (0.59) MEN1KMT2AKDM4CTP53HPGD
SCHEMBL5118077 0.87 MEN1 (0.59) MEN1KMT2AKDM4CTP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3835289-A1 SULFUR-CONTAINING POLYMERIZABLE MONOMER AND USE THEREOF Sun Medical Co., Ltd. (JP) 2021-06-16 EP disclosed
US-9682996-B2 Alpha helix mimetic compositions for treating cancer and other CBP/catenin-mediated diseases and conditions Prism BioLab Co., Ltd. (JP) 2017-06-20 US disclosed
US-20150376204-A1 ALPHA HELIX MIMETIC COMPOSITIONS FOR TREATING CANCER AND OTHER CBP/CATENIN-MEDIATED DISEASES AND CONDITIONS Prism BioLab Co., Ltd. (JP) 2015-12-31 US disclosed
US-9126981-B2 Alpha helix mimetic compositions for treating cancer and other CBP/catenin-mediated diseases and conditions Prism BioLab Co., Ltd. (JP) 2015-09-08 US disclosed
US-20140221657-A1 ALPHA HELIX MIMETIC COMPOSITIONS FOR TREATING CANCER AND OTHER CBP/CATENIN-MEDIATED DISEASES AND CONDITIONS PRISM BIOLAB CORPORATION (JP) 2014-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150376204-A1 ALPHA HELIX MIMETIC COMPOSITIONS FOR TREATING CANCER AND OTHER CBP/CATENIN-MEDIATED DISEASES AND CONDITIONS CREBBP, CTNNB1, CTNNA1 MEN1 2962/4885KMT2A 1322/4885KDM4C 1681/4885
US-20140221657-A1 ALPHA HELIX MIMETIC COMPOSITIONS FOR TREATING CANCER AND OTHER CBP/CATENIN-MEDIATED DISEASES AND CONDITIONS CREBBP, CTNNB1, CTNNA1 MEN1 2962/4885KMT2A 1322/4885KDM4C 1681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.