Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.34 |
| ▸ | SELE | P16581 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788 | 1.00 | MEN1 (0.53) | MEN1KMT2AKDM4CPOLBLMNA | |
| SCHEMBL15914347 | 0.97 | KMT2A (0.53) | MEN1KMT2AKDM4CPOLBLMNA | |
| SCHEMBL10704936 | 0.95 | MEN1 (0.56) | MEN1KMT2AKDM4CPOLBLMNA | |
| SCHEMBL9731947 | 0.95 | MEN1 (0.56) | MEN1KMT2AKDM4CPOLBLMNA | |
| SCHEMBL15914379 | 0.95 | MEN1 (0.56) | MEN1KMT2AKDM4CPOLBLMNA | |
| SCHEMBL15914955 | 0.95 | MEN1 (0.56) | MEN1KMT2AKDM4CPOLBLMNA | |
| SCHEMBL11539684 | 0.92 | MEN1 (0.48) | MEN1KMT2AKDM4CPOLBLMNA | |
| SCHEMBL24776345 | 0.87 | MEN1 (0.57) | MEN1KMT2AKDM4CPOLBLMNA | |
| SCHEMBL3280586 | 0.87 | MEN1 (0.53) | MEN1KMT2AKDM4CPOLBLMNA | |
| SCHEMBL6879144 | 0.85 | MEN1 (0.52) | MEN1KMT2AKDM4CPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019038362-A1 | ANTIBACTERIAL PYRROLOIMIDAZOLONES | IDORSIA PHARMACEUTICALS LTD (CH) | 2019-02-28 | — | — | WO | disclosed |