SCHEMBL15915440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27499027	0.83	TSHR (0.52)	TSHRCYP3A4CYP2C9CYP2C19POLB
	SCHEMBL29973515	0.82	TSHR (0.66)	TSHRCYP3A4CYP2C9CYP2C19POLB
	SCHEMBL15917236	0.82	TSHR (0.71)	TSHRCYP3A4CYP2C9CYP2C19POLB
	SCHEMBL3087652	0.81	POLB (0.59)	TSHRCYP3A4CYP2C9CYP2C19POLB
	SCHEMBL15916754	0.81	TSHR (0.75)	TSHRCYP3A4CYP2C9CYP2C19POLB
	SCHEMBL15916530	0.81	TSHR (0.75)	TSHRCYP3A4CYP2C9CYP2C19POLB
	SCHEMBL23864377	0.80	CYP3A4 (0.49)	TSHRCYP3A4CYP2C9CYP2C19EPHX2
	SCHEMBL15924957	0.78	TSHR (0.51)	TSHRCYP3A4CYP2C9CYP2C19POLB
	SCHEMBL20627051	0.78	POLB (0.53)	TSHRCYP3A4CYP2C9CYP2C19POLB
	SCHEMBL30754609	0.78	USP2 (0.51)	TSHRCYP3A4CYP2C9CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.