Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.56 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.56 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | EEF2K | O00418 | 1/20 | 0.39 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | NEK4 | P51957 | 1/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11771862 | 0.85 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2TSHRHSD17B10 | |
| SCHEMBL4886981 | 0.84 | TXNRD1 (0.57) | TXNRD1TXNRD3TXNRD2TSHRCYP3A4 | |
| SCHEMBL35153 | 0.81 | TXNRD1 (0.58) | TXNRD1TXNRD3TXNRD2HSD17B10RPS6KA3 | |
| SCHEMBL21358790 | 0.80 | TXNRD1 (0.58) | TXNRD1TXNRD3TXNRD2CYP3A4TDP1 | |
| Ammonia Solution, Strong SCHEMBL11281990 | 0.79 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2HSD17B10RPS6KA3 | |
| SCHEMBL21192750 | 0.79 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2HSD17B10RPS6KA3 | |
| SCHEMBL901181 | 0.79 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2HSD17B10RPS6KA3 | |
| Ammonia Solution, Strong SCHEMBL10606612 | 0.79 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2HSD17B10RPS6KA3 | |
| SCHEMBL11318738 | 0.79 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2HSD17B10RPS6KA3 | |
| 2,6-Dichlorophenol SCHEMBL1030875 | 0.79 | TXNRD1 (0.63) | TXNRD1TXNRD3TXNRD2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579312-B2 | Method for treating/preventing disease using cognitive ability of cerebrum and pharmaceutical | SYSTEM C (JP) | 2017-02-28 | — | — | US | disclosed |
| US-20150320735-A1 | METHOD FOR TREATING/PREVENTING DISEASE USING COGNITIVE ABILITY OF CEREBRUM AND PHARMACEUTICAL | SYSTEM C (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20110092548-A1 | METHOD FOR TREATING/PREVENTING DISEASE USING COGNITIVE ABILITY OF CEREBRUM AND PHARMACEUTICAL | MINOWADA TAKURO | 2011-04-21 | — | — | US | disclosed |
| EP-2005956-A1 | METHOD FOR TREATING/PREVENTING DISEASE USING COGNITIVE ABILITY OF CEREBRUM AND PHARMACEUTICAL | Minowada, Takuro (JP) | 2008-12-24 | — | — | EP | disclosed |