Cyclohexylamine

Cyclohexylamine

SCHEMBL15918671

C[C@H](NS(=O)(=O)c1cccc2c(N(C)C)cccc12)C(=O)O.NC1CCCCC1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
F2 P00734 4/20 0.54
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
NLRP3 Q96P20 1/20 0.46
TYMS P04818 1/20 0.46
CA2 P00918 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL30763312 1.00 F2 (0.54) F2PRSS1PRSS2PRSS3NLRP3
Cyclohexylamine SCHEMBL29197249 1.00 F2 (0.54) F2PRSS1PRSS2PRSS3NLRP3
SCHEMBL29683331 0.88 F2 (0.55) F2PRSS1PRSS2PRSS3CA2
SCHEMBL867347 0.88 F2 (0.55) F2PRSS1PRSS2PRSS3CA2
SCHEMBL867346 0.88 F2 (0.55) F2PRSS1PRSS2PRSS3CA2
Cyclohexylamine SCHEMBL30852798 0.85 SLC1A3 (0.54) F2
Cyclohexylamine SCHEMBL1169027 0.84 F2 (0.55) F2
Cyclohexylamine SCHEMBL1169023 0.84 F2 (0.55) F2
Cyclohexylamine SCHEMBL25313860 0.83 F2 (0.54) F2TYMS
Cyclohexylamine SCHEMBL6239195 0.83 F2 (0.66) F2TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250277200-A1 ENGINEERED CPN1 CONSTRUCTS AND VARIANTS VERTEX PHARMACEUTICALS INCORPORATED 2025-09-04 US disclosed
CN-117440822-A Engineered CPN1 constructs and variants 弗特克斯药品有限公司 2024-01-23 CN disclosed
EP-4284416-A1 ENGINEERED CPN1 CONSTRUCTS AND VARIANTS Vertex Pharmaceuticals Incorporated (US) 2023-12-06 EP disclosed
US-20190300824-A1 BACTERIAL SPORE COMPOSITIONS FOR INDUSTRIAL USES ENVERA LIC, LLC (US) 2019-10-03 US disclosed
US-10308909-B2 Dried spore germinative compound mixtures ENVERA LIC, LLC (US) 2019-06-04 US disclosed
EP-2954041-B1 DRIED SPORE GERMINATIVE COMPOUND MIXTURES ENVERA LLC (US) 2018-08-29 EP disclosed
US-9932543-B2 Bacterial spore compositions for industrial uses ENVERA, LLC (US) 2018-04-03 US disclosed
US-20160362654-A1 DRIED SPORE GERMINATIVE COMPOUND MIXTURES ENVERA, LLC (US) 2016-12-15 US disclosed
US-9447376-B2 Dried spore germinative compound mixtures ENVERA, LLC (US) 2016-09-20 US disclosed
US-20160040119-A1 BACTERIAL SPORE COMPOSITIONS FOR INDUSTRIAL USES ENVERA, LLC (US) 2016-02-11 US disclosed
US-20160037781-A1 BACTERIAL SPORE COMPOSITIONS FOR INDUSTRIAL USES ENVERA, LLC (US) 2016-02-11 US disclosed
EP-2954041-A1 DRIED SPORE GERMINATIVE COMPOUND MIXTURES Envera LLC (US) 2015-12-16 EP disclosed
WO-2014124120-A1 DRIED SPORE GERMINATIVE COMPOUND MIXTURES ENVERA, LLC (US) 2014-08-14 WO disclosed
US-20140220662-A1 DRIED SPORE GERMINATIVE COMPOUND MIXTURES ENVERA, LLC (US) 2014-08-07 US disclosed