Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18825349 | 0.82 | LMNA (0.41) | TSHRLMNATRPA1ALDH1A1ALOX15 | |
| SCHEMBL15866376 | 0.80 | LMNA (0.32) | TSHRLMNA | |
| SCHEMBL12909964 | 0.78 | LMNA (0.66) | TSHRLMNATRPA1ALDH1A1ALOX15 | |
| SCHEMBL1783157 | 0.78 | LMNA (0.66) | TSHRLMNATRPA1ALDH1A1ALOX15 | |
| SCHEMBL15450107 | 0.78 | LMNA (0.66) | TSHRLMNATRPA1ALDH1A1ALOX15 | |
| SCHEMBL10688271 | 0.76 | LMNA (0.43) | TSHRLMNATRPA1ALDH1A1ALOX15 | |
| SCHEMBL13093731 | 0.76 | TSHR (0.43) | TSHRLMNATRPA1ALDH1A1ALOX15 | |
| SCHEMBL23091547 | 0.75 | TSHR (0.48) | TSHRALDH1A1ALOX15MEN1KMT2A | |
| SCHEMBL20437876 | 0.74 | LMNA (0.42) | TSHRLMNATRPA1ALDH1A1ALOX15 | |
| SCHEMBL16860521 | 0.73 | LMNA (0.41) | TSHRLMNATRPA1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117090-A1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS, INC. (US) | 2014-07-31 | — | — | WO | disclosed |