Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.55 |
| ▸ | FAAH | O00519 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919871 | 0.90 | NPY2R (0.62) | MAPTKDM4EALDH1A1LMNAPOLB | |
| SCHEMBL15920276 | 0.83 | MAPT (0.70) | MAPTKDM4EALDH1A1THRBFAAH | |
| SCHEMBL15920163 | 0.78 | NPY2R (0.76) | MAPTTHRBFAAHPOLBSMN1; SMN2 | |
| SCHEMBL15919996 | 0.76 | NPY2R (0.77) | MAPTKDM4ELMNATHRBFAAH | |
| SCHEMBL15920278 | 0.75 | MAPT (0.54) | MAPTKDM4EALDH1A1LMNATHRB | |
| SCHEMBL15920002 | 0.74 | NPC1 (0.65) | MAPTKDM4ELMNATHRBFAAH | |
| SCHEMBL15920284 | 0.73 | CYP2C9 (0.63) | MAPTKDM4EALDH1A1LMNATHRB | |
| SCHEMBL27647454 | 0.71 | KMT2A (0.61) | MAPTALDH1A1LMNATHRBFAAH | |
| SCHEMBL5421806 | 0.71 | KMT2A (0.61) | MAPTKDM4ELMNATHRBFAAH | |
| SCHEMBL1574931 | 0.71 | SMN1; SMN2 (0.64) | MAPTTHRBFAAHHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |