Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.76 |
| ▸ | FAAH | O00519 | 4/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.53 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.53 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.53 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15919857 | 0.87 | MAPT (0.70) | NPY2RFAAHNPC1RAB9AMAPT | |
| SCHEMBL15919866 | 0.86 | NPY2R (1.00) | NPY2RMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15920167 | 0.85 | FAAH (0.64) | NPY2RFAAHMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL15920165 | 0.84 | CACNA2D1 (0.68) | FAAHMAPTNPSR1KMT2AMEN1 | |
| SCHEMBL15920168 | 0.83 | CACNA2D1 (0.61) | FAAHNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL15920183 | 0.82 | MAPT (0.64) | NPY2RMAPTKMT2AMEN1POLB | |
| SCHEMBL15920269 | 0.81 | CA12 (0.64) | MAPTNPSR1KMT2AMEN1CNR1 | |
| SCHEMBL15920162 | 0.80 | FAAH (0.60) | FAAHNPSR1KMT2AMEN1CNR1 | |
| SCHEMBL15920276 | 0.79 | MAPT (0.70) | FAAHNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL15919872 | 0.78 | MAPT (0.59) | FAAHNPC1RAB9AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014116684-A1 | NON-PEPTIDIC NEUROPEPTIDE Y RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2014-07-31 | — | — | WO | disclosed |