Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 8/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.70 |
| ▸ | COMT | P21964 | 2/20 | 0.70 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | RECQL | P46063 | 1/20 | 0.68 |
| ▸ | EGFR | P00533 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8848281 | 0.88 | FTO (0.74) | FTOMEN1KMT2AGPR35COMT | |
| SCHEMBL8848272 | 0.88 | FTO (0.74) | FTOMEN1KMT2AGPR35COMT | |
| SCHEMBL8848276 | 0.88 | FTO (0.74) | FTOMEN1KMT2AGPR35COMT | |
| SCHEMBL20100865 | 0.88 | FTO (0.74) | FTOMEN1KMT2AGPR35COMT | |
| SCHEMBL28720710 | 0.86 | FTO (0.73) | FTOMEN1KMT2AGPR35COMT | |
| SCHEMBL20100868 | 0.86 | FTO (0.73) | FTOMEN1KMT2AGPR35COMT | |
| SCHEMBL16680886 | 0.86 | FTO (0.73) | FTOMEN1KMT2AGPR35COMT | |
| SCHEMBL4940495 | 0.86 | FTO (0.73) | FTOMEN1KMT2AGPR35COMT | |
| SCHEMBL4940498 | 0.86 | FTO (0.73) | FTOMEN1KMT2AGPR35COMT | |
| SCHEMBL29493672 | 0.86 | FTO (0.80) | FTOMEN1KMT2AGPR35COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014115098-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF NEUROLOGICAL DISEASES AND INFLAMMATION | KANDULA MAHESH (IN) | 2014-07-31 | — | — | WO | disclosed |