Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29450844 | 0.87 | — | — | |
| SCHEMBL132853 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL27933765 | 0.85 | TSHR (0.46) | TSHRSMN1; SMN2GAAMKNK1MKNK2 | |
| Hydrochloric Acid SCHEMBL6441917 | 0.85 | TSHR (0.46) | TSHRSMN1; SMN2GAAMKNK1MKNK2 | |
| SCHEMBL18836883 | 0.83 | TSHR (0.41) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL1564270 | 0.82 | PLA2G7 (0.50) | TSHRSMN1; SMN2GAAPLA2G7CYP11B1 | |
| SCHEMBL24167640 | 0.80 | CYP3A4 (0.56) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL15920609 | 0.80 | TSHR (0.39) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL18459203 | 0.80 | CYP11B1 (0.54) | TSHRSMN1; SMN2HDAC1HDAC6CYP11B1 | |
| SCHEMBL29887750 | 0.80 | CYP3A4 (0.56) | TSHRSMN1; SMN2GAAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014114186-A1 | JNK INHIBITORS | 山东亨利医药科技有限责任公司 (CN) | 2014-07-31 | — | — | WO | disclosed |