Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15544448 | 0.89 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL28547135 | 0.87 | GSK3B (0.50) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL7920331 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL45823 | 0.82 | KDM4E (0.67) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL11901698 | 0.82 | KDM4E (0.50) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL5335630 | 0.82 | CA12 (0.59) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL31386371 | 0.81 | PDGFRB (0.43) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL28125731 | 0.81 | GSK3B (0.50) | MAPTGSK3BKMT2AHPGDS | |
| SCHEMBL15544203 | 0.81 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL30985101 | 0.81 | MAPT (0.54) | KDM4EALDH1A1MAPTHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4727591-A1 | SMARCA2 DEGRADERS AND USES THEREOF | Astrazeneca AB (SE) | 2026-04-22 | — | — | EP | disclosed |
| WO-2024256988-A1 | SMARCA2 DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2024-12-19 | — | — | WO | disclosed |
| US-20230406851-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2023-12-21 | — | — | US | disclosed |
| EP-3998267-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | Bellus Health Cough Inc. (CA) | 2022-05-18 | — | — | EP | disclosed |
| US-20220062290-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2022-03-03 | — | — | US | disclosed |
| US-20220062290-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2022-03-03 | — | — | US | disclosed |
| EP-3381917-B1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | BELLUS HEALTH COUGH INC (CA) | 2021-09-08 | — | — | EP | disclosed |
| EP-3381917-B1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | BELLUS HEALTH COUGH INC (CA) | 2021-09-08 | — | — | EP | disclosed |
| US-20210228588-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2021-07-29 | — | — | US | disclosed |
| US-20210228588-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2021-07-29 | — | — | US | disclosed |
| US-20170143730-A1 | Imidazopyridine Compounds and Uses Thereof | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2017-05-25 | — | — | US | disclosed |
| US-20170143730-A1 | Imidazopyridine Compounds and Uses Thereof | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2017-05-25 | — | — | US | disclosed |
| US-9598409-B2 | Imidazopyridine compounds and uses thereof | NEOMED INSTITUTE (CA) | 2017-03-21 | — | — | US | disclosed |
| US-9598409-B2 | Imidazopyridine compounds and uses thereof | NEOMED INSTITUTE (CA) | 2017-03-21 | — | — | US | disclosed |
| US-9598409-B2 | Imidazopyridine compounds and uses thereof | NEOMED INSTITUTE (CA) | 2017-03-21 | — | — | US | disclosed |
| US-20150361078-A1 | Imidazopyridine Compounds and Uses Thereof | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2015-12-17 | — | — | US | disclosed |
| US-20150361078-A1 | Imidazopyridine Compounds and Uses Thereof | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2015-12-17 | — | — | US | disclosed |
| US-20150361078-A1 | Imidazopyridine Compounds and Uses Thereof | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.3) LIMITED (GB) | 2015-12-17 | — | — | US | disclosed |
| EP-2951177-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | Neomed Institute (CA) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014117274-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | NEOMED INSTITUTE (CA) | 2014-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230406851-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | NISCH, ABL1, PAICS | KDM4E 1264/4885ALDH1A1 664/4885MAPT 2247/4885 |
| US-20150361078-A1 | Imidazopyridine Compounds and Uses Thereof | NISCH, ABL1, PAICS | KDM4E 1264/4885ALDH1A1 664/4885MAPT 2247/4885 |
| US-20220062290-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | NISCH, ABL1, PAICS | KDM4E 1264/4885ALDH1A1 664/4885MAPT 2247/4885 |
| US-20170143730-A1 | Imidazopyridine Compounds and Uses Thereof | NISCH, ABL1, PAICS | KDM4E 1264/4885ALDH1A1 664/4885MAPT 2247/4885 |
| US-20210228588-A1 | IMIDAZOPYRIDINE COMPOUNDS AND USES THEREOF | NISCH, ABL1, PAICS | KDM4E 1264/4885ALDH1A1 664/4885MAPT 2247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.