Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.55 |
| ▸ | MAPT | P10636 | 9/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1923366 | 0.83 | ALDH1A1 (0.72) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL1923000 | 0.81 | ALDH1A1 (0.73) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL1923376 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL12156722 | 0.81 | NPC1 (0.58) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL1923694 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL1923385 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL1923002 | 0.81 | ALDH1A1 (0.56) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL6669056 | 0.76 | SMN1; SMN2 (0.75) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL1922861 | 0.76 | KMT2A (0.60) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL1923358 | 0.74 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014120790-A1 | SMALL MOLECULES TO BLOCK SIGNALING PATHWAY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-07 | — | — | WO | claimed |
| WO-2014120790-A1 | SMALL MOLECULES TO BLOCK SIGNALING PATHWAY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014120790-A1 | SMALL MOLECULES TO BLOCK SIGNALING PATHWAY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-08-07 | — | — | WO | disclosed |