Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IP6K1 | Q92551 | 5/20 | 0.42 |
| ▸ | PARP1 | P09874 | 4/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | SYK | P43405 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15922336 | 1.00 | IP6K1 (0.42) | IP6K1PARP1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL4535771 | 0.90 | PIK3CD (0.44) | IP6K1PIK3CDPIK3CAPIK3CBMKNK1 | |
| SCHEMBL4535757 | 0.90 | PIK3CD (0.44) | IP6K1PIK3CDPIK3CAPIK3CBMKNK1 | |
| SCHEMBL13606771 | 0.90 | PIK3CD (0.44) | IP6K1PIK3CDPIK3CAPIK3CBMKNK1 | |
| SCHEMBL30524630 | 0.86 | IP6K1 (0.42) | IP6K1PARP1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL29849333 | 0.86 | IP6K1 (0.42) | IP6K1PARP1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL26113183 | 0.86 | IP6K1 (0.44) | IP6K1PIK3CDPIK3CAPIK3CBMKNK1 | |
| SCHEMBL31352786 | 0.86 | IP6K1 (0.44) | IP6K1PIK3CDPIK3CAPIK3CBMKNK1 | |
| SCHEMBL26113178 | 0.86 | IP6K1 (0.44) | IP6K1PIK3CDPIK3CAPIK3CBMKNK1 | |
| SCHEMBL13606776 | 0.83 | PIK3CD (0.43) | IP6K1PIK3CDPIK3CAPIK3CBMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150368230-A1 | RADIOLABELED QUINAZOLINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-12-24 | — | — | US | disclosed |
| US-20150368230-A1 | RADIOLABELED QUINAZOLINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-12-24 | — | — | US | disclosed |
| US-20150368230-A1 | RADIOLABELED QUINAZOLINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-12-24 | — | — | US | disclosed |
| EP-2951171-A1 | RADIOLABELED QUINAZOLINE DERIVATIVES | Boehringer Ingelheim International GmbH (DE) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014118197-A1 | RADIOLABELED QUINAZOLINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368230-A1 | RADIOLABELED QUINAZOLINE DERIVATIVES | ERBB2, EGFR, ERBB4 | IP6K1 1150/4885PARP1 973/4885PIK3CD 292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.