Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | IP6K1 | Q92551 | 5/20 | 0.40 |
| ▸ | IP6K3 | Q96PC2 | 2/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535757 | 1.00 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBERBB2EPHA2 | |
| SCHEMBL13606771 | 1.00 | PIK3CD (0.44) | PIK3CDPIK3CAPIK3CBERBB2EPHA2 | |
| SCHEMBL13606776 | 0.93 | PIK3CD (0.43) | PIK3CDPIK3CAPIK3CBERBB2EPHA2 | |
| SCHEMBL13606773 | 0.92 | PIK3CD (0.49) | PIK3CDPIK3CAPIK3CBIP6K1IP6K3 | |
| SCHEMBL31352786 | 0.90 | IP6K1 (0.44) | PIK3CDPIK3CAPIK3CBERBB2EPHA2 | |
| SCHEMBL30524630 | 0.90 | IP6K1 (0.42) | PIK3CDPIK3CAPIK3CBERBB2EPHA2 | |
| SCHEMBL26113178 | 0.90 | IP6K1 (0.44) | PIK3CDPIK3CAPIK3CBERBB2EPHA2 | |
| SCHEMBL29849333 | 0.90 | IP6K1 (0.42) | PIK3CDPIK3CAPIK3CBERBB2EPHA2 | |
| SCHEMBL26113183 | 0.90 | IP6K1 (0.44) | PIK3CDPIK3CAPIK3CBERBB2EPHA2 | |
| SCHEMBL15922336 | 0.90 | IP6K1 (0.42) | PIK3CDPIK3CAPIK3CBERBB2EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090306105-A1 | Bicyclic heterocycles, medicaments containing these compounds, their use and process for preparing them | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-12-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306105-A1 | Bicyclic heterocycles, medicaments containing these compounds, their use and process for preparing them | BPHL, CYP11B2, MAP3K1 | PIK3CD 769/4885PIK3CA 489/4885PIK3CB 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.