SCHEMBL15924657

SCHEMBL15924657

Cc1c(-c2ccccc2S(N)(=O)=O)ccc(-c2cnc(N)nc2)c1F

nearest known ligand 0.64

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX5AP P20292 19/20 0.64
FEN1 P39748 19/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18059768 0.78 ALOX5AP (0.69) ALOX5APFEN1
SCHEMBL15932372 0.78 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15917213 0.77 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL15915698 0.75 ALOX5AP (1.00) ALOX5APFEN1
SCHEMBL18059767 0.75 ALOX5AP (0.48) ALOX5APFEN1
SCHEMBL15918296 0.74 ALOX5AP (0.61) ALOX5APFEN1
Trifluoroacetic Acid SCHEMBL15917168 0.73 ALOX5AP (0.83) ALOX5APFEN1
SCHEMBL15924656 0.72 ALOX5AP (0.72) ALOX5APFEN1
SCHEMBL3833421 0.71 ALOX5AP (0.56) ALOX5APFEN1
Trifluoroacetic Acid SCHEMBL15917910 0.71 ALOX5AP (0.85) ALOX5APFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2951170-A2 FLAP MODULATORS Janssen Pharmaceutica, N.V. (BE) 2015-12-09 EP claimed
WO-2014121055-A2 FLAP MODULATORS JANSSEN PHARMACEUTICA NV (BE) 2014-08-07 WO claimed