Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL27547121 | 0.94 | TSHR (0.67) | TSHRCA5ACA5BTP53CYP2C9 | |
| Cadaverine Tartrate SCHEMBL27491776 | 0.91 | TSHR (0.62) | TSHRCA5ACA5BTP53CYP2C9 | |
| Cadaverine Tartrate SCHEMBL988008 | 0.91 | TSHR (0.71) | TSHRCA5ACA5BTP53CYP2C9 | |
| Cadaverine Tartrate SCHEMBL6009350 | 0.88 | TSHR (0.59) | TSHRCA5ACA5BTP53CYP2C9 | |
| Cadaverine Tartrate SCHEMBL27906745 | 0.88 | TSHR (0.67) | TSHRCA5ACA5BTP53CYP2C9 | |
| Cadaverine Tartrate SCHEMBL9345627 | 0.85 | TSHR (0.62) | TSHRCA5ACA5BTP53CYP2C9 | |
| Cadaverine Tartrate SCHEMBL9345632 | 0.85 | TSHR (0.62) | TSHRCA5ACA5BTP53CYP2C9 | |
| Cadaverine Tartrate SCHEMBL27906743 | 0.85 | TSHR (0.62) | TSHRCA5ACA5BTP53CYP2C9 | |
| Cadaverine Tartrate SCHEMBL10390162 | 0.84 | TSHR (0.83) | TSHRTP53CYP2C9PDE4ANFKB1 | |
| Cadaverine Tartrate SCHEMBL14058907 | 0.84 | TSHR (0.83) | TSHRTP53CYP2C9PDE4ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2967077-A2 | NETWORK-BASED MICROBIAL COMPOSITIONS AND METHODS | Seres Therapeutics, Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2951285-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF PATHOGENIC BACTERIAL GROWTH | Seres Therapeutics, Inc. (US) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014145958-A2 | NETWORK-BASED MICROBIAL COMPOSITIONS AND METHODS | Seres Health, Inc. (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014121301-A1 | COMPOSITIONS AND METHODS FOR INHIBITION OF PATHOGENIC BACTERIAL GROWTH | Seres Health, Inc. (US) | 2014-08-07 | — | — | WO | disclosed |