Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15916426 | 1.00 | ALOX5AP (0.77) | ALOX5APFEN1 | |
| SCHEMBL15915354 | 0.87 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL20538667 | 0.87 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL15915975 | 0.87 | ALOX5AP (1.00) | ALOX5APFEN1 | |
| SCHEMBL15916737 | 0.86 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL15916538 | 0.86 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL20538692 | 0.86 | FEN1 (1.00) | ALOX5APFEN1 | |
| SCHEMBL21089055 | 0.83 | FEN1 (0.68) | ALOX5APFEN1 | |
| SCHEMBL15916373 | 0.82 | FEN1 (0.74) | ALOX5APFEN1 | |
| SCHEMBL15915638 | 0.79 | FEN1 (0.66) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951170-B1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-10-24 | — | — | EP | claimed |
| EP-3495359-A1 | FLAP MODULATORS | Janssen Pharmaceutica NV (BE) | 2019-06-12 | — | — | EP | disclosed |
| EP-3070085-B1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-09 | — | — | EP | disclosed |
| EP-2951170-A2 | FLAP MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014121055-A2 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-07 | — | — | WO | disclosed |