⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7108389 | 0.69 | — | — | |
| SCHEMBL28960719 | 0.62 | — | — | |
| SCHEMBL12706333 | 0.62 | — | — | |
| SCHEMBL27499532 | 0.55 | — | — | |
| SCHEMBL1567748 | 0.54 | — | — | |
| SCHEMBL1256267 | 0.54 | — | — | |
| SCHEMBL13214267 | 0.54 | — | — | |
| SCHEMBL27478170 | 0.54 | — | — | |
| SCHEMBL29778183 | 0.54 | — | — | |
| SCHEMBL2632451 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951170-A2 | FLAP MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014121055-A2 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-07 | — | — | WO | disclosed |