⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27499532 | 0.78 | — | — | |
| SCHEMBL11497889 | 0.76 | — | — | |
| SCHEMBL27395751 | 0.73 | — | — | |
| SCHEMBL1256267 | 0.71 | — | — | |
| SCHEMBL27478170 | 0.71 | — | — | |
| SCHEMBL4378842 | 0.71 | MAPT (0.30) | — | |
| SCHEMBL30616596 | 0.68 | — | — | |
| SCHEMBL29042986 | 0.67 | — | — | |
| SCHEMBL11355322 | 0.67 | — | — | |
| SCHEMBL14536626 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438108-B1 | PHENYL [A]INDOLE[2,3-G]QUINOLIZINE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2022-08-10 | — | — | EP | claimed |
| US-20240091310-A1 | COMPOSITIONS AND METHODS USEFUL FOR THE PREVENTION AND/OR TREATMENT OF DISEASE IN MAMMALS | Viro-Gen (Pty) Ltd (ZA) | 2024-03-21 | — | — | US | disclosed |
| EP-4178604-A1 | COMPOSITIONS AND METHODS USEFUL FOR THE PREVENTION AND/OR TREATMENT OF DISEASE IN MAMMALS | Viro-Gen (Pty) Ltd (ZA) | 2023-05-17 | — | — | EP | disclosed |
| EP-3438108-B1 | PHENYL [A]INDOLE[2,3-G]QUINOLIZINE COMPOUNDS, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS THEREOF | SHANGHAI INST MATERIA MEDICA CAS (CN) | 2022-08-10 | — | — | EP | disclosed |