Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 13/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298349 | 0.90 | PIK3CD (0.57) | PIN1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL627722 | 0.89 | PIK3CD (0.59) | PIN1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL15925454 | 0.84 | PIK3CD (0.48) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL15925455 | 0.83 | AR (0.52) | PIN1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL10288616 | 0.82 | PIK3CD (0.48) | PIN1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL10288310 | 0.81 | PIK3CD (0.50) | PIK3CDPIK3CBPIK3CGPIK3CACYP3A4 | |
| SCHEMBL15925480 | 0.81 | CETP (0.41) | PIN1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL10298371 | 0.80 | PIK3CD (0.62) | PIN1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL624581 | 0.80 | PIN1 (0.41) | PIN1PIK3CDPIK3CBPIK3CGPIK3CA | |
| SCHEMBL10288324 | 0.79 | PIK3CD (0.50) | PIN1PIK3CDPIK3CBPIK3CGPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150175563-A1 | HETEROARYLS AND USES THEREOF | MILLENNIUM PHARM INC (US) | 2015-06-25 | — | — | US | disclosed |
| US-8796268-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150175563-A1 | HETEROARYLS AND USES THEREOF | PIK3R1, PIK3R2, PIK3R3 | PIN1 622/4885PIK3CD 18/4885PIK3CB 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.