Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | RAB9A | P51151 | 3/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | NPC1 | O15118 | 2/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.75 |
| ▸ | LCLAT1 | Q6UWP7 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | KDM4A | O75164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13571264 | 0.91 | LMNA (0.84) | LMNAKMT2ARAB9AALOX12SMN1; SMN2 | |
| SCHEMBL13571003 | 0.88 | LMNA (0.78) | LMNAKMT2ARAB9AALOX12SMN1; SMN2 | |
| SCHEMBL13570833 | 0.88 | LMNA (0.78) | LMNAKMT2ARAB9AALOX12SMN1; SMN2 | |
| SCHEMBL29848608 | 0.86 | LMNA (0.75) | LMNAKMT2ARAB9AALOX12SMN1; SMN2 | |
| SCHEMBL13571530 | 0.86 | LMNA (0.75) | LMNAKMT2ARAB9AALOX12SMN1; SMN2 | |
| SCHEMBL16383899 | 0.85 | LCLAT1 (0.84) | LMNAKMT2ARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL20597937 | 0.85 | KDM4E (0.79) | LMNAKMT2ARAB9AALOX12SMN1; SMN2 | |
| SCHEMBL12490865 | 0.85 | LMNA (0.73) | LMNAKMT2ARAB9AALOX12SMN1; SMN2 | |
| SCHEMBL13571014 | 0.85 | LMNA (0.73) | LMNAKMT2ARAB9AALOX12SMN1; SMN2 | |
| SCHEMBL13570912 | 0.84 | LMNA (0.72) | LMNAKMT2ARAB9AALOX12SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796320-B2 | 1,3,4-Oxadiazole-2-carboxamide compound | GENERAL INCORPORATED ASSOCIATION PHARMA VALLEY PROJECT SUPPORTING ORGANIZATION (JP) | 2014-08-05 | — | — | US | disclosed |