Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 20/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166781 | 0.92 | CXCR3 (0.52) | CXCR3KCNH2 | |
| SCHEMBL165135 | 0.84 | CXCR3 (0.55) | CXCR3KCNH2 | |
| SCHEMBL163847 | 0.83 | CXCR3 (0.50) | CXCR3KCNH2 | |
| SCHEMBL115167 | 0.82 | CXCR3 (0.37) | CXCR3 | |
| SCHEMBL162241 | 0.81 | CXCR3 (0.52) | CXCR3KCNH2 | |
| SCHEMBL165291 | 0.81 | HCRTR1 (0.38) | CXCR3 | |
| SCHEMBL164590 | 0.81 | CXCR3 (0.52) | CXCR3KCNH2 | |
| SCHEMBL15911221 | 0.81 | CXCR3 (0.37) | CXCR3 | |
| SCHEMBL164089 | 0.80 | PREP (0.39) | CXCR3 | |
| SCHEMBL113350 | 0.79 | CXCR3 (0.51) | CXCR3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424840-B1 | CXCR3 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2014-08-06 | — | — | EP | disclosed |