Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16303822 | 1.00 | BRD4 (0.49) | BRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL9974006 | 0.84 | BRD4 (0.54) | BRD4SLC6A2SLC6A3 | |
| SCHEMBL21966250 | 0.82 | BRD4 (0.69) | BRD4 | |
| SCHEMBL9974002 | 0.82 | BRD4 (0.69) | BRD4 | |
| SCHEMBL16306561 | 0.82 | BRD4 (0.46) | BRD4 | |
| SCHEMBL15926491 | 0.82 | BRD4 (0.46) | BRD4 | |
| SCHEMBL15925891 | 0.81 | BRD4 (0.62) | BRD4 | |
| SCHEMBL16303824 | 0.81 | BRD4 (0.59) | BRD4 | |
| SCHEMBL15925880 | 0.81 | BRD4 (0.59) | BRD4 | |
| SCHEMBL14756077 | 0.81 | BRD4 (0.74) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796261-B2 | Bromodomain inhibitors and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |
| US-8796261-B2 | Bromodomain inhibitors and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2014-08-05 | — | — | US | disclosed |