Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.64 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | KLK1 | P06870 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1675255 | 0.88 | F10 (0.83) | F10F2KLK1 | |
| SCHEMBL8359004 | 0.84 | F10 (0.75) | F10F2KLK1 | |
| SCHEMBL15911452 | 0.82 | F10 (0.69) | F10F2KLK1 | |
| SCHEMBL3966835 | 0.81 | CCR2 (0.55) | F10F2KLK1 | |
| SCHEMBL1674972 | 0.80 | F10 (0.72) | F10F2KLK1 | |
| SCHEMBL8358667 | 0.79 | F10 (0.63) | F10F2KLK1 | |
| SCHEMBL1675102 | 0.79 | F10 (0.80) | F10F2KLK1 | |
| SCHEMBL1675027 | 0.78 | F10 (0.68) | F10F2KLK1 | |
| SCHEMBL1675120 | 0.78 | F10 (1.00) | F10F2KLK1 | |
| SCHEMBL1674956 | 0.77 | F10 (1.00) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451185-B1 | INDOLE-2-CARBOXAMIDES AS FACTOR XA INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2014-08-06 | — | — | EP | disclosed |