Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 2/20 | 0.49 |
| ▸ | RARB | P10826 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.45 |
| ▸ | GSK3B | P49841 | 12/20 | 0.43 |
| ▸ | GNG2 | P59768 | 1/20 | 0.36 |
| ▸ | GNB1 | P62873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23797248 | 1.00 | RARG (0.49) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL15927479 | 0.83 | RARG (0.52) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL16527140 | 0.81 | RARG (0.50) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL9586810 | 0.81 | RARG (0.50) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL10170776 | 0.79 | PTPN1 (0.47) | PTPN1GSK3BGNG2GNB1 | |
| SCHEMBL10215425 | 0.79 | PTPN1 (0.39) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL1422581 | 0.79 | RARG (0.66) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL1782019 | 0.79 | RARG (0.66) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL1782039 | 0.79 | RARG (0.66) | RARGRARBCHRNB2CHRNA4CHRNA1 | |
| SCHEMBL18527168 | 0.79 | GSK3B (0.49) | PTPN1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014119617-A1 | AMIDINE COMPOUND AND SALT THEREOF | 富山化学工業株式会社 (JP) | 2014-08-07 | — | — | WO | disclosed |