Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 2/20 | 0.50 |
| ▸ | RARB | P10826 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.48 |
| ▸ | CHRNG | P07510 | 1/20 | 0.48 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | CHRND | Q07001 | 1/20 | 0.48 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.43 |
| ▸ | PDE4A | P27815 | 4/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15927479 | 0.87 | RARG (0.52) | RARGRARBHPGDCHRNA1CHRNG | |
| SCHEMBL9586810 | 0.84 | RARG (0.50) | RARGRARBHPGDCHRNA1CHRNG | |
| SCHEMBL23797248 | 0.81 | RARG (0.49) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL15927449 | 0.81 | RARG (0.49) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL10932919 | 0.78 | CHRNB2 (0.73) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL14428708 | 0.77 | HPGD (0.47) | HPGDHSD17B3SMN1; SMN2GAAPDE4D | |
| SCHEMBL9586643 | 0.77 | RARG (0.49) | RARGRARBHPGDCHRNA1CHRNG | |
| SCHEMBL1782019 | 0.76 | RARG (0.66) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL1422581 | 0.76 | RARG (0.66) | RARGRARBCHRNA1CHRNGCHRNB1 | |
| SCHEMBL1782039 | 0.76 | RARG (0.66) | RARGRARBCHRNA1CHRNGCHRNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015025962-A1 | AMIDINE COMPOUND OR SALT THEREOF | 富山化学工業株式会社 (JP) | 2015-02-26 | — | — | WO | disclosed |